How much is a flight from Mayaguez to Panama City?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Mayaguez and Panama City.

Pick a travel date to see today’s available fares.

Fares change often — checking several times throughout the week can make a big difference. Booking in advance often means access to lower prices for the Mayaguez - Panama City route.

Which airports near Mayaguez or Panama City offer flights?

In many cases, using a nearby airport can improve your chances of finding direct flights or better rates.

• Airports in Mayaguez: Only Mayaguez - Eugenio Maria de Hostos is currently operating.
• Airports in Panama City: 2 options available in Panama City - Pacífico International Airport, Paitilla.

Secondary airports can offer faster travel thanks to shorter lines and quicker boarding times than major ones.

Find flights from Mayaguez to Panama City that suit your schedule

Use Jetcost to sort and filter results based on your preferred flight time, number of stops, price range, or airline. View deals from the best airlines and travel agencies.

Other popular destinations

Interested in Panama? These cities are also in demand: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

Connecting flights can be cheaper but often mean longer layovers. You can easily select either direct or connecting flights with a single click using the filters.