What’s the cost of a flight from Mexico City to Santa Cruz de la Sierra?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Mexico City and Santa Cruz.

Choose a date to explore the best fares now.

If possible, avoid holiday periods: ticket prices tend to rise quickly and availability drops, especially on busy routes. Morning and evening flights are often in high demand too — book early to get a good fare.

Flying between Mexico City and Santa Cruz? Consider these airports

Depending on your destination and where you’re starting from, it might make sense to look beyond the main hubs.

• Airports in Mexico City: You can fly from either Mexico City - International or International.
• Airports in Santa Cruz: Besides Santa Cruz - Viru Viru, also consider Santa Cruz.

Check if your destination airport has a rail link — it can make getting around easier. Jetcost lets you view options from all Mexico City airports in a single search.

Smart ways to search flights from Mexico City to Santa Cruz de la Sierra

Use Jetcost to view tailored results based on what you care about — time, duration, number of stops, or even your preferred booking agency. Results include the best airlines and travel agencies.

Other popular destinations

Flying to Bolivia? Other travelers also searched: Cochabamba, La Paz, Santa Cruz, Sucre, Tarija.

Prefer non-stop flights? Just activate the filter to skip unnecessary layovers. If your dates are flexible, you can also explore different departure and return combinations to find the best fit.