How much should you expect to spend for a flight from San Francisco to Panama City?

Flight prices from San Francisco to Panama City change depending on demand and time of booking.

Pick a travel date to see today’s available fares.

Studies show that flying midweek — like on a Tuesday or Wednesday — can be cheaper than weekend flights. Still, airfares change frequently, so check updated prices on Jetcost.

Flying from or to San Francisco and Panama City? Here are your airport options

Knowing your full list of nearby airports can make flight planning easier, especially when routes vary.

• Airports in San Francisco: Only San Francisco is available for departures.
• Airports in Panama City: Arrivals into Panama City are possible from 2 airports - Pacífico International Airport, Paitilla.

For families or those traveling with assistance, smaller airports can be easier to navigate. Cities served by multiple airports often allow for more flexible travel planning.

Adjust your flight filters for San Francisco – Panama City

Jetcost gives you tools to search smarter. Pick your ideal price range, airline, departure time, and flight type — then compare offers from the best travel agencies and carriers.

Other popular destinations

Planning a trip to Panama? These cities are popular too: Bocas Del Toro, Changuinola, David, Panama City, Puerto Obaldia.

Sorting options let you see the most affordable flights first. Some results may include extra fees shown only at checkout — always read carefully to see what’s included.